Endocrine Abstracts

Introduction: Maturity onset diabetes of the young (MODY) is a group of monogenic, autosomal, dominant diseases characterized by a single genetic mutation that results in beta-cells disfunction with consequent hyperglycemia. It Accounts for 1-5% of all cases of diabetes. At the moment, optimal treatment has not been established and it relies on the individual response. A mutation of NEUROD1 gene, a transcription factor expressed by pancreatic and nervous tissues, has been foun...